General Information

Job Advert Title: Senior Associate - Associate Manager, GT-RTO, Innovation & Technology(遺伝子治療技術研究)

Location: Tsukuba, Ibaraki

Division: Gene Therapy Research & Technical Operations

Employment Class: Permanent


Purpose & Scope

Astellas Gene Therapies(AGT)は、生命を脅かす重篤かつ稀な病気をもつ患者のための遺伝子治療を開発しています。つくば研究センターにてGene Therapy Research(GTR)のメンバーとして、革新的な遺伝子治療パイプラインの構築を共に目指していただける方を募集いたします。具体的には、シニアマネージャーの指示の下、遺伝子調節技術、配列設計とベクター構築、およびin vitro評価構築をおこなっていただき、遺伝子治療候補品の創出に貢献していただきます。

Astellas Gene Therapies (AGT) is developing genetic medicines for patients with rare, life-threatening diseases. This position will work as a member of Gene Therapy Research (GTR) in the laboratory in Tsukuba to contribute to the creation of innovative gene therapy pipelines. The scope of the position is to create the candidate of gene therapy products for multiple research programs by followings under direction of senior manager, developing the gene regulation technology, sequence design and vector construction, and in vitro evaluation.

Essential Job Responsibilities



•ベクター配列の設計と構築、およびPCR、qPCR / ddPCR、WB、ELISA等を用いたセルベースアッセイによるin vitro評価をおこないます





・Make research plan for creating the candidate gene therapy product for research program in cooperation with GTR-IT and research project team members

Select or develop appropriate gene regulation technology with a deep understanding of biology of disease target gene and multiple technologies

Vector sequence design and construction, and cell-based in vitro evaluation including but not limited to PCR, qPCR/ddPCR, WB, ELISA

Analyzes data, interpret, summarize and present it to project team members to contribute decision making

Understand the latest technologies in gene therapy, which are rapidly developing and expanding

Be an active member of scientific team, contributing to the overall conversation, debate, and scientific direction of the group

Adhere to research ethics and compliance


・PhD in molecular biology or life sciences

Experience in gene therapy related research or gene regulation technology

English skill required for working in a global team. Have a TOEIC score around 800 or of another test score that is expected to be equivalent.


・Technical proficiency in cell and molecular biology techniques, vector sequence design and construction, and cell-based assay

Highly self-motivated, goal oriented, able to perform in a highly team-oriented environment, and possess good problem-solving skills

Strong written and verbal communication skills, with the ability to clearly articulate complex concepts and strategies

Business level communication skill in English

Attitude/characteristics of "Find a Way, Care Deeply, Get Stuff Done" and operates with transparency, being trust


・Be familiar with multiple areas of biology and technologies

Be familiar with ophthalmology or experience in ophthalmology research 

Experience working in global, cross-functional team consisting of different backgrounds

Experience in patent application or patent search

Experience in collaboration research with academia/biotech or evaluation of external opportunities

【勤務地 / Location

茨城県つくば市 アステラス製薬 つくば研究センター

Tsukuba, Ibaraki

【勤務開始日 / Start Date


Will be decided according to the candidate's flexibility

【契約期間 / Contract Duration


Not limited to specified period

【試用期間 / Probation Period


No probation period in principle

【給与 / Salary




①Base salary: will be decided by the candidate's experience, skill and capability.

②When Discretionary Work System is applied: Discretionary work allowance will be paid.(50,000~100,000yen, based on the Grade)

③When Flextime System is applied: Overtime allowance will be paid for time worked in excess of prescribed working hours.

【昇給 / Salary Raise


Once a year

【賞与 / Bonus


Twice a year (July, December)

【諸手当 / Allowance

裁量労働手当、住宅手当、通勤手当 等

Discretionary work allowance, Housing allowance, Commutation allowance, etc.

【勤務時間 / Working Hours

8:30~17:30(月~木)、8:3015:45(金)、専門業務型 裁量労働制



Discretionary Work System

【休日 / Holidays


Weekends(Sat and Sun), holidays, May 1st, summer vacation, New Year holidays

【休暇 / Vacation Leave

年次有給休暇、育児休業制度、介護休業制度 等

Annual paid leave, childcare leave system, nursing care leave system, etc.

【福利厚生 / Welfare

雇用保険、労災保険、厚生年金、健康保険、共済会制度、社宅制度、持株会制度、財形貯蓄制度 等

Employment Insurance, Industrial Accident Compensation Insurance, Welfare Pension Insurance, Health Insurance, Mutual Aid Association System, Company Housing System, Employee Shareholder Association System, Property Accumulation Savings System

【お問い合わせ / Contact

アステラス製薬株式会社 採用担当 / Japan Recruiting team, Astellas Pharma Inc.


"We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law."