General Information

Job Advert Title: Manager, Pharmacologist(がん免疫研究)

Location: Tsukuba, Ibaraki

Division: Immuno-Oncology

Employment Class: Permanent


Purpose & Scope

Recent advances in drug discovery targeting cancer have been remarkable, and Astellas is constantly challenging next-generation modalities such as cell therapy, gene therapy, and multifunctional antibodies, as well as new cancer biology. Under such circumstances, we have successfully delivered innovative treatment drugs such as XOSPATA, XTANDI, and PADCEV to cancer patients. Furthermore, we are currently promoting drug discovery research by combining multifunctional modality and the biological understanding of TME in the Primary Focus "Immuno-Oncology" established though our Focus Area approach.


We are urgently recruiting people who will participate in the challenge of driving a paradigm shift in cancer treatment together with our team. We welcome applications from those who can persistently plan and carry out research with innovative ideas and a spirit of challenge, and lead research projects as a member of the global team.

Essential Job Responsibilities

The position is expected to lead and support drug discovery for cancer treatment and will be in charge of the following tasks,


1. Design and perform animal studies, especially using tumor-bearing mice, which include efficacy studies, mechanism-of-action (MoA) analysis, etc. Then, analyze the data and provide stakeholders with data interpretation.

2. Document study results and data interpretation to be submitted to the regulatory agencies.

3. Develop, characterize and improve animal models to better understand disease and drug MoA in collaboration with external facilities.

4. Manage CROs (in Japan and overseas) for pharmacology studies.


Experience of animal studies using tumor-bearing mice

Advanced knowledge and experience in drug discovery

Skills of cell-culture, flow cytometry, ELISA, qPCR, immunohistochemistry, ELISPOT and western blot.

Writing and verbal communication skill in English.


PhD with 5+ years or MS with 8+ years of relevant experience in life science.

Work experience in collaboration with research team members at pharmaceutical companies and biotech companies


Experience of recombinant oncolytic viruses.

Experience working in global, cross-functional team consisting of different backgrounds.

Skills of multiplexed gene expression analysis such as Nanostrings, RNAseq.

Skills of multiplex-immunohistochemistry.

Business level skills in English.

【勤務地 / Location

茨城県つくば市 アステラス製薬 つくば研究センター

Tsukuba, Ibaraki

【勤務開始日 / Start Date


Will be decided according to the candidate's flexibility

【契約期間 / Contract Duration


Not limited to specified period

【試用期間 / Probation Period


No probation period in principle

【給与 / Salary




①Base salary: will be decided by the candidate's experience, skill and capability.

②When Discretionary Work System is applied: Discretionary work allowance will be paid.(50,000~100,000yen, based on the Grade)

③When Flextime System is applied: Overtime allowance will be paid for time worked in excess of prescribed working hours.

【昇給 / Salary Raise


Once a year

【賞与 / Bonus


Twice a year (July, December)

【諸手当 / Allowance

裁量労働手当、住宅手当、通勤手当 等

Discretionary work allowance, Housing allowance, Commutation allowance, etc.

【勤務時間 / Working Hours

8:30~17:30(月~木)、8:3015:45(金)、専門業務型 裁量労働制



Discretionary Work System

【休日 / Holidays


Weekends(Sat and Sun), holidays, May 1st, summer vacation, New Year holidays

【休暇 / Vacation Leave

年次有給休暇、育児休業制度、介護休業制度 等

Annual paid leave, childcare leave system, nursing care leave system, etc.

【福利厚生 / Welfare

雇用保険、労災保険、厚生年金、健康保険、共済会制度、社宅制度、持株会制度、財形貯蓄制度 等

Employment Insurance, Industrial Accident Compensation Insurance, Welfare Pension Insurance, Health Insurance, Mutual Aid Association System, Company Housing System, Employee Shareholder Association System, Property Accumulation Savings System

【お問い合わせ / Contact

アステラス製薬株式会社 採用担当 / Japan Recruiting team, Astellas Pharma Inc.


"We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law."