Job Advert Title: CNS Scientist, Discovery Bioscience, Gene Therapy Research & Technical Operations
Location: Tsukuba, Ibaraki
Division: Gene Therapy Research & Technical Operations
Employment Class: Permanent
Description
【募集の背景 / Purpose & Scope】
The primary purpose of this position is to contribute to the creation of innovative gene therapy pipelines by conducting valuable in vivo studies and engaging in discussion with stakeholders including scientific and business perspectives. Research areas span multiple therapeutic areas including CNS diseases, and expertise with CNS disease models is desirable.
Candidate will work as a member of Exploratory Animal Studies unit of Discovery Bioscience in Gene Therapy Research and Technical Operations (GT-RTO), and will work in the laboratory in Tsukuba.
【職務の内容 / Essential Job Responsibilities】
（雇入れ直後）
• Make research plan and implement in vivo evaluation in rodents (sometimes NHPs) for creating gene therapy product candidate in cooperation with Discovery Bioscience members and research project team members.
• Conduct in vitro bioanalysis evaluation including but not limited to qPCR, WB, ELISA
• Lead specific gene therapy project with other stakeholders and manage whole progress of project including works in Discovery Bioscience as divisional lead (DB Lead).
• Stay current with the latest information on biology, disease, gene therapy technology and competitors appropriately.
• Mentor and provide guidance to junior research scientist as needed.
• Engage in cross-functional communication and present findings to internal and external stakeholders.
• Curate documentation and maintain detailed records of data processing procedures and results.
• Perform quality control checks to ensure accurate and reliable results.
（変更の範囲）
会社内での全ての業務
【就業環境に関する要件 / Specific Physical or Environmental Requirements】
• This position is a hands-on laboratory-based position that required onsite work.
• Most of members in Discovery Bioscience in Tsukuba are Japanese, but we work communicating with relevant members in other research units in GT-RTO located in the US who are non-Japanese.
【応募要件 / Qualifications】
＜必須 / Must＞
• PhD in medicine, pharmacology, molecular biology, or other related fields.
• 5+ years of experience in in vivo research including expertise in CNS disease research and mouse models.
• No objection to conducting experiments on large animals such as NHPs.
• Experience of general in vitro work related to in vivo studies including cell culture, qPCR and immunohistochemistry.
• English and Japanese communication skill required for working in a global team.
• Ability to perform in a highly team-oriented environment, be self-driven, and possess good problem-solving skills.
• Ability to build strong relationship with co-workers of various backgrounds and expertise.
• Deep understanding about the importance of research ethics/compliance.
＜歓迎 / Want＞
• 3+ years of PostDoc or beyond as CNS scientist with experience in evaluating animal models involving expertise in mouse behavioral test battery.
• Experience working for gene therapies using Adeno-Associated Virus (AAV)
• Experience leading research project team in pharma or academia.
• Experience working with a multinational team of scientists.
• Experience working on neuromuscular, ophthalmology, and/or Cardiac research.
【応募書類 / Application Documents】
和文履歴書（必須）・和文職務経歴書（必須）・英文レジュメ（任意）
Resumes
【選考プロセス / Selection details】
書類選考 → 1次面接 → 適性検査 → 最終面接
※変更の可能性もございますので、予めご了承下さい。
CV screening → First interview → Aptitude test → Final interview
*Please be advised that there might be a change in the process.
【勤務地 / Location】
（雇入れ直後）
茨城県つくば市 アステラス製薬 つくば研究センター
Tsukuba, Ibaraki
※ＪＲひたち野うしく駅とつくばエクスプレス（TX) 研究学園駅より通勤バスがございます。
（変更の範囲）
会社の定める事業場および自宅
【勤務開始日 / Start Date】
応相談
Will be decided according to the candidate's flexibility
【契約期間 / Contract Duration】
期間の定めなし
Not limited to specified period
【試用期間 / Probation Period】
試用期間原則なし
No probation period in principle
【給与 / Salary】
①基本給：当人の経歴・技術・技能等を考慮して決定
②裁量労働制の場合：裁量労働手当として職務グレードに応じて50,000～100,000円支給
③フレックスタイム制の場合：月間の所定労働時間を超えて勤務する時間に対して時間外勤務手当を支給
①Base salary: will be decided by the candidate's experience, skill and capability.
②When Discretionary Work System is applied: Discretionary work allowance will be paid.(50,000～100,000yen, based on the Grade)
③When Flextime System is applied: Overtime allowance will be paid for time worked in excess of prescribed working hours.
【昇給 / Salary Raise】
有り
【賞与 / Bonus】
有り
【諸手当 / Allowance】
裁量労働手当、住宅手当、通勤手当 等
Discretionary work allowance, Housing allowance, Commutation allowance, etc.
【勤務時間 / Working Hours】
8:30～17:30（月～木）、8:30～15:45（金）、裁量労働制
裁量労働制の場合、所定労働時間を働いたものとみなす。
8:30～17:30（Mon～Thu）、8:30～15:45（Fri）
Discretionary Work System
【休日 / Holidays】
完全週休２日制（土曜・日曜）、祝日、5月1日、夏季、年末年始
Weekends(Sat and Sun), holidays, May 1st, summer vacation, New Year holidays
【休暇 / Vacation Leave】
年次有給休暇、育児休業制度、介護休業制度 等
Annual paid leave, childcare leave system, nursing care leave system, etc.
【福利厚生 / Welfare】
雇用保険、労災保険、厚生年金、健康保険、共済会制度、社宅制度、持株会制度、財形貯蓄制度 等
Employment Insurance, Industrial Accident Compensation Insurance, Welfare Pension Insurance, Health Insurance, Mutual Aid Association System, Company Housing System, Employee Shareholder Association System, Property Accumulation Savings System
【アステラス製薬 採用サイト/ Career web site】
https://re-jp.astellas.com/jp/recruit/newgraduates/
For more information about Astellas, please visit our career web site.
"We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law."
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